Anakinra for flares of pyogenic arthritis in PAPA syndrome

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منابع مشابه

Fever of undetermined origin in a patient with pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA syndrome).

Address to: Dr. José Roberto Lambertucci. Depto Clínica Médica/Serviço de Doenças Infecciosas e Parasitárias/UFMG. Av. Alfredo Balena 190, 30130-100 Belo Horizonte, MG, Brasil. Phone: 55 31 3337-7781; Fax: 55 31 3409-9820 e-mail: [email protected] Received 4 January 2014 Accepted 22 January 2014 A 22-year-old man was referred to our clinic with a history of recurrent fever, arthalgia, and swell...

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Little is known about the influence of pregnancy on pyogenic sterile arthritis, pyoderma gangrenosum, acne (PAPA) syndrome. We experienced a rare case of pregnancy complicated with PAPA syndrome. The patient had various histories of skin and joint disorders and experienced subarachnoid hemorrhage during pregnancy; however, her skin lesion was unaffected.

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PReS-FINAL-2238: PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome: results from the Eurofever registry

Results In February 2013 baseline and clinical information were available of 2567 patients from 88 centers in the Eurofever registry. Of these 16 patients PAPA patients (M:F = 8:8), from 3 different centers, fulfilled the inclusion criteria and were therefore analysed: 10 were of the same family, in 3 patients the disease was caused by a de novo mutation while in 3 cases the mutation was found ...

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Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.

Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne Syndrome (PAPA syndrome) is an autoinflammatory disease caused by aberrant production of the proinflammatory cytokine interleukin-1. Mutations in the gene encoding proline serine threonine phosphatase-interacting protein-1 (PSTPIP1) have been linked to PAPA syndrome. PSTPIP1 is an adaptor protein that interacts with PYRIN, the protein encoded b...

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Successful combined antibiotic therapy with oral clindamycin and oral rifampicin for pyoderma gangrenosum in patient with PASH syndrome

HS: hidradenitis suppurativa IL: interleukin PAPA: pyoderma gangrenosum with pyogenic sterile arthritis and cystic acne PAPASH: pyoderma gangrenosum with pyogenic sterile arthritis, acne, and hidradenitis suppurativa PASH: pyoderma gangrenosum with cystic acne and hidradenitis suppurativa PG: pyoderma gangrenosum INTRODUCTION Pyoderma gangrenosum (PG) is a neutrophilic dermatitis, the prevalenc...

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ژورنال

عنوان ژورنال: Rheumatology

سال: 2005

ISSN: 1460-2172

DOI: 10.1093/rheumatology/keh479